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Vitamin D3 400iu


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Dosage range

1-3 capsules daily, or as advised by your health care practitioner. Ideally taken with food. It is advisable that this dose be taken in increments throughout the day rather than all at once, due to the fact that hepatic hydroxylase, the enzyme involved in the conversion of D3 into 25(OH)D3 can quickly reach a saturation point, at which it is unable to perform the conversion.


Potential applications

Osteoporosis, osteomalacia (bone softening), muscle weakness/wasting, cellular support, heart disease, stroke, hypertension, autoimmune diseases, depression, chronic pain, osteoarthritis, psoriasis, and periodontal disease. Hyperparathyroidism due to low levels of vitamin D. Vitamin D malabsorption is common in Crohn’s Disease and can lead to a deficiency of the vitamin.

Vitamin D deficiency results in rickets in children and osteomalacia in adults. Rickets, characterised by an inability to calcify the bone matrix, results in softening of the skull bones, bowing of the legs, spinal curvature, and increased joint size. Vitamin D deficiency is now most often seen in elderly people who do not get any sunlight, particularly those in nursing homes.


Known contraindications - People with hyperparathyroidism should not take vitamin D without consulting a physician.



Vitamin D should be used with caution in patients taking digoxin, because hypercalcemia (which may result with excess vitamin D use) may precipitate abnormal heart rhythms.

Concurrent administration of thiazide diuretics and vitamin D to hypoparathyroid patients may cause hypercalcemia, which may be transient or may require discontinuation of vitamin D. Stimulant laxatives can reduce dietary vitamin D absorption. Use of corticosteroids can cause osteoporosis and calcium depletion with long-term administration. This calcium depletion creates a greater need for both supplemental calcium and vitamin D (which is necessary for calcium absorption).


Pregnancy and lactation - Recommendations for vitamin D in pregnancy, at the time of writing, are set at 10ug (400iu) daily. Doses higher than 10ug should be via consultation with a GP.


Useful links - Osteoporosis: Calcium, magnesium and boron powder, organic flax seed oil, Synbiotic Daily (improves calcium metabolism).