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High Twelve® B12 with B Complex




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400-800ug daily. Folic acid is well tolerated and can be used at high doses, however it may cause increased flatulence, nausea and loss of appetite.


Potential applications

The main applications of folic acid are prevention of neural tube defects, atherosclerosis (reduces elevated homocysteine levels), osteoporosis, and cervical dysplasia. Other applications include depression, anemia,

crohn’s disease, fatigue, restless leg syndrome, epilepsy, fatigue, and infertility.


Known Contraindications

High doses of folic acid should be used with caution in epileptics as it may increase the risk of seizures. Those with allergy or intolerance to citrus fruits including lemons should not use, or use with caution.


Ingredients: Per Capsule:

Methylcobalamin 500ug

Adenocyanocobalamin 500ug

In a base of alfalfa, spirulina and bilberry


Recommended use: Those following a vegetarian or vegan lifestyle, the elderly, those taking diabetic medication, neuropathy, fatigue, cognition and mood.


Safety: Generally considered safe and well tolerated. Not recommended during pregnancy or lactation


Contraindications : None known.


Drug interactions : Folic acid may mask B12 deficiency (25). Those on anti-diabetic drugs such as Metformin should supplement with B12 and folic acid (26). Contraceptive drugs can deplete B12 levels (reference [this may be only in older, higher dose OCP]).

Disclaimer: Viridian Nutrition has a strict no animal testing policy with a fixed cut-off date of December 1st, 1999. The Viridian Nutrition specific ingredient supply chain does not fund animal research and studies cited here are for informational purposes only.